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LXA4 suppresses the activation of the NF-κB pathway. Detection of NF-κBp65 nuclear protein levels in (A) rat lung tissues and (B) RAW264.7 cells by western blot analysis. Observation of total IκBα and p-IκBα protein in (C) rat lungs and (D) RAW264.7 cells. Data are presented as the means ± SD (n=10 in vivo, n=6 in vitro). #P<0.05 vs. the CON group. *P<0.05 vs. the PQ group. ns, not significant (P>0.05) vs. the CON group. LXA4, lipoxin A4; PQ, paraquat.
