Table 10.
Clinical Utility of Substance Use Disorder Screeners Compared with Diagnostic Assessment
| Study | Screening Measure | Cut Point | Sensitivity % | Specificity % | PPV | NPV | Prevalence % | N |
|---|---|---|---|---|---|---|---|---|
| Smith et al., 2009171 | Single-question alcohol screening test | ≥1 | 0.82 | 0.79 | 11.5 | 286 | ||
| Smith et al., 2010172 | Single-question screening test for drug use and drug use disorders (illicit and nonmedical use of prescription drugs) | ≥1 | 1.00 | 0.74 | 11.9 | 286 | ||
| Brown and Rounds, 1995174 | CAGE-AID | ≥1 ≥2 | 0.79, 0.77 | 0.77, 0.85 | ||||
| Brown et al., 2001175 | TICS | 0.79 | 0.78 | 23 | 434, 702 | |||
| Bradley et al., 2007176 | AUDIT-C for men and women | 0.86, 0.73 | 0.89, 0.91 | |||||
| Gryczynski et al., 2017176 | TAPS | 0.80, 0.85, 0.91, 0.85 | 0.92, 0.71, 0.89, 0.93 | 0.60, 0.44, 0.25, 0.49 | 0.97, 0.95, 1.0, 0.99 | 25, 14, 4, 17 | 1,995- 2,000 |
Abbreviations: PPV, positive predictive value; NPV, negative predictive value; CAGE-AID, CAGE Adapted to Include Drugs; TICS, Two-Item Conjoint Screening test; AUDIT-C, Alcohol Use Disorders Identification Test- Consumption; TAPS, Tobacco, Alcohol, Prescription Medication, and Other Substance use.