Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 12;5(6):1605–1616. doi: 10.1182/bloodadvances.2020003658

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by The American Society of Hematology

PMC Copyright notice

Figure 6. — MMP-low HSCs contain more fragmented mitochondria. (Ai) Representative 3-dimensional immunofluorescent confocal images of TOM20 (red, TOM20; blue, DAPI; scale bar, 1 μm). (Aii) The total number of mitochondrial fragments per cell. (Aiii-Aiv) The average area and volume per fragment of mitochondria in each cell. (B) Representative 3-dimensional immunofluorescent confocal images (left) of DRP1 (green, DRP1; blue, DAPI; scale bar, 1 μm) and quantification (right) of fluorescence intensity of localized DRP1 foci above threshold. (C) Two-dimensional immunofluorescent confocal images (left; scale bar, 5 μm) of TOM20 (red), DRP1 (green), DAPI (blue), merged (yellow); inset contains magnified images, quantification of colocalization of TOM20 and DRP1 (right). All analyses were performed in MMP-low and MMP-high CD90⁺ PB HSCs. Data are presented as mean ± standard deviation; Student t test: *P < .05, **P < .01, ****P < .0001.