Table 2.

EC₅₀ values [nM] of parental antibodies and bispecific Dab-Fc 2 × 3 molecule determined by flow cytometry analysis

	MCF-7 [nM]	BT474 [nM]	SKBR3 [nM]	NCI-N87 [nM]
Trastuzumab	0.7 ± 0.6	1.3 ± 0.4	1.7 ± 0.6	1.2 ± 0.7
IgG 3–43	0.015 ± 0.004	0.012 ± 0.007	0.013 ± 0.001	0.009 ± 0.002
Dab-Fc 2x3	4.1 ± 1.8	4.6 ± 1.5	7.4 ± 4.9	3.3 ± 1.8

Mean ± SD, n = 3.