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LINE-1 DNA methylation and its association with breast tissue folate. (a) DNA methylation among 4 CpG sites in the LINE-1 gene categorized by low vs high breast tissue folate status. (b) Linear regression between breast tissue folate and average DNA methylation in breast tissue from premenopausal women. (c) LINE-1 DNA methylation categorized by low vs high breast tissue folate. **p < 0.01
