Table 1.
Baseline characteristics | N=18 |
Age (years) | |
Median (range) | 71.6 (54–88) |
Race | |
White/Caucasian | 15 |
Black | 3 |
ECOG PS (N, %) | |
0 | 7 |
1 | 11 |
Gleason score | |
Median (range) | 8 (6–9) |
Baseline PSA (ng/mL) (range) | 25.58 (0.62–1006) |
Prior therapies | |
Chemotherapy (CSPC) | 10 |
Chemotherapy (CRPC) | 6 |
Therapeutic cancer vaccine | 7 |
Immune checkpoint inhibitor | 6 |
Abiraterone | 12 |
Enzalutamide | 12 |
PARP inhibitors | 4 |
ADT only (mCRPC treatment-naïve) | 5 |
Number of prior mCRPC therapies | |
Median (range) | 3 (0–7) |
ADT, androgen-deprivation therapy; CRPC, castration-resistant prostate cancer; CSPC, castration-sensitive prostate cancer; ECOG PS, Eastern Cooperative Oncology Group Performance Score; mCRPC, metastatic castration-resistant prostate cancer; PARP, poly ADP ribose polymerase; PSA, prostate-specific antigen.