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. 2020 Oct 28;14(2):536–543. doi: 10.1111/cts.12902

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© 2020 Tango Therapeutics. Clinical and Translational Science published by Wiley Periodicals LLC on behalf of the American Society for Clinical Pharmacology and Therapeutics.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Steady‐state concentration (C_ss)/half‐maximal inhibitory concentration (IC₅₀) values for 25 targeted therapies. Colors represent drug target. Dashed lines are drawn at ratios of 0.3 and 3 to depict a 3‐fold range of plausible values about unity. Data are displayed on a log‐log scale to improve readability.