Table 2.
Genotypes and alleles frequencies of SNPs among 112 women with EOC
| Polymorphisms | rs ID |
Homozygous wild type (%) |
Heterozygous variant n (%) |
Homozygous variant n (%) |
MAF | HWE (p) |
|---|---|---|---|---|---|---|
| GSTP1 c.313A>G | rs1695 | AA 49 (43.8) | AG 44 (39.3) | GG 19 (17.0) | 0.37 | 0.10 |
| ABCB1 c.1236C>T | rs1128503 | CC 38 (33.9) | CT 57 (50.9) | TT 17 (15.2) | 0.41 | 0.56 |
| ABCB1 c.3435C>T | rs1045642 | CC 37 (33.0) | CT 60 (33.0) | TT 15 (13.4) | 0.41 | 0.23 |
| ABCB1 c.2677G>T/A | rs2032582 | GG 40 (35.7) |
GT 50 (44.6) GA 5 (4.5) |
TT 12 (10.7) TA 4 (3.6) AA 1 (0.9) |
0.33a/0.03b | 0.09 |
HWE, deviation from the Hardy–Weinberg equilibrium (χ2‐test); MAF, minor allele frequency; SNP, single‐nucleotide polymorphism.
a
MAF from genotype TT.
b
MAF from genotype AA.