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. 2021 Mar 24;6(1):e000682. doi: 10.1136/tsaco-2021-000682

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Volcano plot. Differentially expressed (DE) proteins are represented in terms of their measured significance of the change (y-axis) and the expression change (x-axis). Dotted lines represent the thresholds used to select the DE genes: 0.6 for expression change and 0.05 for p value. The upregulated proteins (positive log fold change) are shown in red, whereas the downregulated genes are blue. Insignificant proteins are shown in black.