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. 2021 Mar 24;6(1):e000682. doi: 10.1136/tsaco-2021-000682

Table 2.

Gene ontology (GO) molecular functions significantly enriched after valproic acid treatment

GO term # proteins (DE/all) P value
GTP binding 18/51 0.002
GTPase activity 14/38 0.003
Structural constituent of ribosome 9/20 0.004
Clathrin adaptor activity 4/5 0.004
Ionotropic glutamate receptor binding 3/3 0.005
Organic anion transmembrane transporter activity 6/12 0.01
Active transmembrane transport activity 11/27 0.02
Drug transmembrane transporter activity 4/7 0.021
Hexosyl transferase activity 4/7 0.021
6-phosphofructokinase activity 2/2 0.031
Malate dehydrogenase activity 2/2 0.031
Calcium-transporting ATPase activity 2/2 0.031
Voltage-gated anion channel activity 2/2 0.031
Oxaloacetate decarboxylase activity 2/2 0.031
Porin activity 2/2 0.031
G protein-coupled serotonin receptor binding 2/2 0.031
Angiostatin binding 2/2 0.031
Alpha-glucosidase activity 2/2 0.031
Purine ribonucleotide binding 47/178 0.033
Isocitrate dehydrogenase activity 3/5 0.042
GTP-dependent protein binding 3/5 0.042
Potassium ion binding 3/5 0.042

# proteins are the number of proteins differentially expressed in this proteomic data set out of the total number of proteins that contribute to that GO term. P value represents the corrected p value after Elim pruning.