Table 4.
Stratified associations between LDL/HDL cholesterol ratio and NAFLD by gender, age, and FPG
| LDL/HDL cholesterol ratio (Quintile), HR (95%CI) | |||||||
|---|---|---|---|---|---|---|---|
| No. of cases | Q1 | Q2 | Q3 | Q4 | Q5 | P-interaction | |
| Gender | > 0.05 | ||||||
| Female | 393 (46.73%) | Ref | 1.84 (1.13, 3.01) | 2.17 (1.36, 3.47) | 2.17 (1.36, 3.45) | 2.58 (1.64, 4.05) | |
| Male | 448 (53.27%) | 1.08 (0.64, 1.85) | 1.73 (1.07, 2.82) | 1.72 (1.07, 2.77) | 1.84 (1.16, 2.91) | 2.48 (1.59, 3.88) | |
| Age, years | < 0.05 | ||||||
| ≥ 60 | 127 (15.10%) | Ref | 3.31 (1.66, 6.62) | 1.57 (0.73, 3.39) | 1.42 (0.67, 3.01) | 2.23 (1.14, 3.34) | |
| ≥ 45, < 60 | 247 (29.37%) | 1.74 (0.78, 3.87) | 2.05 (0.93, 4.48) | 2.26 (1.07, 4.75) | 2.46 (1.17, 5.16) | 3.50 (1.70, 7.20) | |
| ≥ 30, < 45 | 325 (38.64%) | 1.06 (0.41, 2.72) | 2.26 (0.94, 5.42) | 3.01 (1.27, 7.08) | 3.10 (1.33, 7.20) | 3.30 (1.43, 7.59) | |
| < 30 | 142 (16.88%) | 1.78 (0.57, 5.56) | 1.67 (0.58, 4.80) | 2.66 (0.94, 7.54) | 2.81 (1.04, 7.56) | 3.96 (1.50, 10.46) | |
| FPG, mmol/l | > 0.05 | ||||||
| ≤ 6.1 | 745 (88.59%) | Ref | 1.70 (1.20, 2.41) | 1.97 (1.40, 2.76) | 1.93 (1.38, 2.70) | 2.50 (1.80, 3.47) | |
| > 6.1 | 96 (11.41%) | 2.08 (1.04, 4.19) | 4.16 (2.20, 7.89) | 3.24 (1.86, 5.64) | 3.74 (2.18, 6.39) | 3.96 (2.48, 6.32) | |
Adjusted for TC, TG and BMI; Model III adjusted for gender, age, ALP, GGT, ALT, AST, ALB, GLB, DBIL, CR, UA, FPG, TC, TG, height, BMI, SBP and DBP
Note: the model was not adjusted for the stratification variable
Abbreviations: CI confidence interval, HR hazard ratios, FPG fasting plasma glucose, NAFLD nonalcoholic fatty liver disease