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. 2021 Mar 25;8:23. doi: 10.1186/s40779-021-00314-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Effects of NBP on the time and distance to motor exhaustion of mice and rats under conditions of acute and chronic hypoxia. Time (a) and distance (b) to exhaustion of mice in the forced exercise wheel-track treadmill experiment at 5800 m for 3 days. Time to exhaustion of rats in the treadmill running experiment at 5800 m for 3 days (c) and 20 days (d). ^*P < 0.05 compared with control group; ^#P < 0.05 compared with 60 mg/kg group