Fig. 4.

Differentially abundant CDR3β sequences identified by the method. The top 20 significantly differentially enriched CDR3β sequences during gluten exposure are shown for a CD PBMC and b CD Gut datasets when using nt 4-mer feature vectors. The result obtained using aa 3-mer feature vectors is on c for CD PBMC and d for CD Gut datasets. Abundance is shown in log10 scale, from low abundance (white) to higher abundance (red). GFD treated samples are shown in light blue and gluten exposed samples are shown in orange bars at the top