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. 2020 Dec 25;106(4):e1150–e1162. doi: 10.1210/clinem/dgaa941

Figure 2.

Figure 2.

Meta-analysis of the risk of glucose variability for microvascular complications in ACCORD and VADT. Hazard ratios for each individual study were estimated using fully adjusted models (Model-3 in text). Fixed-effect meta-analysis and inverse variance weighted method was used. Composite outcome: Nephropathy or Retinopathy; Nephropathy: 2 consecutive values of serum creatinine ≥3.3 or eGFR < 30; Retinopathy: Photocoagulation or Vitrectomy.