Table 2:
Clinical response to MDCF-2 or RUSF supplementation
| Anthropometry at the start of intervention i.e. baseline | |||
|---|---|---|---|
| MDCF-2 (n=59)† | RUSF (n=59)† | β Treatment (95% CI)‡ | |
| WLZ | −2.22 ± 0.39 | −2.29 ± 0.36 | 0.086 (−0.056, 0.228) |
| WAZ | −2.66 ± 0.67 | −2.71 ± 0.64 | 0.036 (−0.213, 0.285) |
| LAZ | −2.14 ± 1.14 | −2.13 ± 1.13 | −0.044 (−0.467, 0.380) |
| MUAC (cm) | 12.8 ± 0.51 | 12.7 ± 0.44 | 0.077 (−0.100, 0.254) |
| Rate of growth during intervention (Δ anthropometry/week) | |||
| β growth rate for MDCF-2 (95% CI)§ | β growth rate for RUSF (95% CI)§ | β Interaction (95% CI)¤ | |
| WLZ | 0.021 (0.014, 0.029) | 0.010 (0.003, 0.017) | 0.011 (0.001, 0.021) |
| WAZ | 0.017 (0.012, 0.022) | 0.010 (0.004, 0.015) | 0.008 (0.001, 0.015) |
| LAZ | 0.004 (0.002, 0.007) | 0.005 (0.003, 0.008) | −0.001 (−0.005, 0.003) |
| MUAC (cm) | 0.031 (0.029, 0.034) | 0.029 (0.025, 0.032) | 0.003 (−0.001, 0.007) |
| Rate of growth including the 1-month follow-up (Δ anthropometry/week) | |||
| β growth rate for MDCF-2 (95% CI)§ | β growth rate for RUSF (95% CI)§ | β Interaction (95% CI)¤ | |
| WLZ | 0.010 (0.005, 0.016) | 0.000 (−0.005, 0.006) | 0.010 (0.002, 0.018) |
| WAZ | 0.009 (0.005, 0.013) | 0.001 (−0.003, 0.005) | 0.008 (0.002, 0.013) |
| LAZ | 0.004 (0.002, 0.006) | 0.003 (0.001, 0.006) | 0.000 (−0.003, 0.003) |
| MUAC (cm) | 0.028 (0.026, 0.031) | 0.024 (0.022, 0.027) | 0.004 (0.000, 0.007) |
Values represent the mean ± SD.
Linear model predicting anthropometry at the start of the intervention as a function of treatment group, controlling for baseline age, gender and any illness 7 days prior to starting the intervention. β indicates the mean difference in anthropometry between participants who were assigned to the MDCF-2 and RUSF arms at the start of the intervention. CI, confidence interval.
Mixed effects linear model predicting anthropometry as a function of weeks since starting nutritional supplementation, controlling for the main effects of baseline age, gender, any illness 7 days prior to starting the intervention, and a random intercept for each participant. β indicates the growth rate in unit (anthropometric measure) per week.
Mixed effects linear model predicting anthropometry as a function of the interaction between treatment group and weeks since starting nutritional supplementation, controlling for the main effects of baseline age, gender, any illness 7 days prior to starting the intervention, weeks in the intervention, treatment group, and a random intercept for each participant. β indicates the interaction between treatment and growth rate in unit/week (a positive value indicates a faster growth rate in children receiving MDCF-2).