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. 2021 Feb 26;13(5):7190–7198. doi: 10.18632/aging.202576

Table 1. Characteristics of elderly patients undergoing elective orthopedic surgery according to survival status within one-year.

Variables Patients alive
N=289
Patients died
N=24
All patients
N=313
P
Preoperative variables
Age, years, mean ±SD 73.3 ± 6.9 80.7 ± 7.0 73.9 ± 7.2 < 0.001
Sex (female) 206 (71.3%) 13 (54.2%) 219 (70.0%) 0.079
BMI (kg/m2), median (IQR) 24.5 (22.0, 26.7) 22.5 (20.2, 24.5) 24.3 (21.9, 26.5) 0.009
Education, years, median (IQR) 6.0 (0.0, 9.0) 5.0 (0.0, 12.0) 6.0 (0.0, 9.5) 0.966
Prescription drugs, n 2 (1, 3) 3 (1, 5) 2 (1, 3) 0.029
ASA Grade < 0.001
ASA I 7 (2.4 %) 0 (0.0 %) 7 (2.2%)
ASA II 174 (60.2 %) 1 (4.2 %) 175 (55.9%)
ASA III 105 (36.3 %) 19 (79.2 %) 124 (39.6%)
ASA IV 3 (1.0 %) 4 (16.7 %) 7 (2.2%)
MMSE, points, median (IQR) 21 (17, 25) 15 (12, 18) 21 (17, 25) < 0.001
Charlson comorbidity index, points, median (IQR) 1 (0, 2) 3 (2, 5) 1 (0, 2) < 0.001
BADL, points, median (IQR) 2 (0, 7) 11 (5, 12) 2 (0, 8) < 0.001
IADL, points, median (IQR) 8 (6, 12) 17 (12, 21) 8 (6, 13) < 0.001
CFS, points, median (IQR) 3 (2, 5) 6 (4, 7) 3 (2, 5) < 0.001
Alb (g/L), mean ±SD 38.1 ± 4.0 36.0 ± 3.5 37.9 ± 4.0 0.014
Hb (g/L), mean ±SD 126.1 ± 16.7 112.5 ± 20.7 125.0 ± 17.4 < 0.001
PLT (×109/L), mean ±SD 212 ± 64 182 ± 63 210 ± 64 0.030
CRP (g/L), median (IQR) 2.2 (0.5, 15.7) 23.3 (1.2, 56.5) 2.3 (0.5, 18.9) 0.004
IL-6 (ng/L), median (IQR) 7.3 (2.8, 15.5) 20.5 (10.6, 33.5) 8.1 (2.9, 18.6) 0.001
Intraoperative variables
Amount of blood loss (ml), median (IQR) 200 (120, 250) 265 (200, 350) 200 (120, 280) 0.007
Duration of surgery (min), median (IQR) 75 (60, 95) 78 (60, 106) 75 (60, 95) 0.660
Type of anesthesia (general anesthesia) 72 (24.9%) 5 (20.8%) 77 (24.6%) 0.656
Postoperative variables
Post-operative delirium 41 (14.2%) 14 (58.3%) 55 (17.6%) < 0.001
Length of stay, days, median (IQR) 7 (6, 9) 10 (7, 13) 7 (6, 9) 0.001
30-d Readmission 19 (6.6 %) 5 (23.8 %) 24 (7.7 %) 0.015
30-d CCI, points, mean ± SD 0.0 (0.0, 25.7) 38.2 (23.0, 56.3) 0.0 (0.0, 29.6) < 0.001

Abbreviation: SD, Standard deviation; IQR, interquartile range; BMI, body mass index; ASA Grade, American Society of Anesthesiologists Grade; MMSE, mini-mental state examination; BADL, basic activities of daily living; IADL, instrumental activities of daily living; CFS, the Clinical Frailty Score; Alb, albumin; Hb, hemoglobin; PLT, platelet; CRP, C-reactive protein; IL-6, interleukin-6; 30-d Readmission, 30-day readmission; 30-d CCI, 30-day comprehensive complication index.