| Gene Symbol |
Biological Process (GO) |
Cellular Component (GO) |
Molecular Function (GO) |
KEGG Pathway |
| UHRF1 |
GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:0010912 positive regulation of isomerase activity |
GO:0005720 nuclear heterochromatin;GO:0000791 euchromatin;GO:0016363 nuclear matrix |
GO:0044729 hemi-methylated DNA-binding;GO:0031493 nucleosomal histone binding;GO:0008327 methyl-CpG binding |
|
| EZH2 |
GO:0098532 histone H3-K27 trimethylation;GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration;GO:0036333 hepatocyte homeostasis |
GO:0035098 ESC/E(Z) complex;GO:0045120 pronucleus;GO:0035097 histone methyltransferase complex |
GO:0046976 histone methyltransferase activity (H3-K27 specific);GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding;GO:0018024 histone-lysine N-methyltransferase activity |
(hsa00310)Lysine degradation; (hsa05206)MicroRNAs in cancer |
| SUV39H2 |
GO:0036123 histone H3-K9 dimethylation;GO:0036124 histone H3-K9 trimethylation;GO:0051567 histone H3-K9 methylation |
GO:0000775 chromosome, centromeric region;GO:0098687 chromosomal region;GO:0000785 chromatin |
GO:0046974 histone methyltransferase activity (H3-K9 specific);GO:0018024 histone-lysine N-methyltransferase activity;GO:1904047 S-adenosyl-L-methionine binding |
(hsa00310)Lysine degradation |
| PCNA |
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:1902990 mitotic telomere maintenance via semi-conservative replication;GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint |
GO:0043626 PCNA complex;GO:0070557 PCNA-p21 complex;GO:0044796 DNA polymerase processivity factor complex |
GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity;GO:0032139 dinucleotide insertion or deletion binding;GO:0000700 mismatch base pair DNA N-glycosylase activity |
(hsa03430)Mismatch repair; (hsa03410)Base excision repair; (hsa03030)DNA replication |
| WHSC1 |
GO:0048298 positive regulation of isotype switching to IgA isotypes;GO:0048296 regulation of isotype switching to IgA isotypes;GO:0048290 isotype switching to IgA isotypes |
GO:0000785 chromatin;GO:0044427 chromosomal part;GO:0005694 chromosome |
GO:0042799 histone methyltransferase activity (H4-K20 specific);GO:0046975 histone methyltransferase activity (H3-K36 specific);GO:0018024 histone-lysine N-methyltransferase activity |
(hsa00310)Lysine degradation; (hsa05202)Transcriptional misregulation in cancer |
| RAD54L |
GO:0000733 DNA strand renaturation;GO:0045003 double-strand break repair via synthesis-dependent strand annealing;GO:0007131 reciprocal meiotic recombination |
GO:0005654 nucleoplasm;GO:0031981 nuclear lumen;GO:0070013 intracellular organelle lumen |
GO:0015616 DNA translocase activity;GO:0036310 annealing helicase activity;GO:0097617 annealing activity |
(hsa03440)Homologous recombination |
