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. 2021 Mar 3;13(5):7570–7588. doi: 10.18632/aging.202620

Figure 5.

Figure 5

Correlations of NLRP1 expression with immune infiltration levels in LUAD. (A, B) The expression levels of NLRP1 in the TCGA-LUAD and GSE72094 datasets had significant positive correlations with the infiltration levels of B cells, CD4 T cells, CD8 T cells, dendritic cells, macrophages and neutrophils. (C, D) The expression of NLRP1 had a significant positive correlation with the immune score of LUAD samples based on the ESTIMATE algorithm in the TCGA-LUAD and GSE72094 datasets. (E, F) Kaplan-Meier survival curve analysis showed that patients with a higher immune score had longer overall survival time than those with a lower immune score in the TCGA-LUAD and GSE72094 datasets. (G, H) Kaplan-Meier survival curve analysis showed that patients with a higher NLRP1 expression level had longer overall survival time than those with a low expression level in the TCGA-LUAD and GSE72094 datasets.