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. 2021 Mar 3;13(5):7570–7588. doi: 10.18632/aging.202620

Table 1. Univariate and multivariate cox regression analyses for OS in LUAD patients.

Variables Univariate analysis Multivariate analysis
No. of patients HR (95% CI) p-value No. of patients HR (95% CI) p-value
Age
≤55 vs. >55 77/367 0.969(0.787−1.193) 0.765
Gender
Female vs. Male 244/200 1.086(0.790−1.492) 0.613
T stage
T1/2 vs.3/4 387/55 1.533(1.241−1.894) <0.001 265/41 1.255(0.967−1.629) 0.087
N stage
N0 vs. N1 286/147 2.818(2.037−3.898) <0.001 195/111 2.123(1.348−3.345) 0.001
M stage
M0 vs. M1 295/23 1.994(1.137−3.497) 0.016 286/20 1.121(0.570−2.206) 0.741
Pathological stage
Stage I/II vs. III/IV 339/97 2.707(11.936−3.786) <0.001 231/75 1.521(0.880−2.629) 0.133
NLRP1
High vs. low expression 222/222 0.694(0.555−0.868) 0.001 153/153 0.713(0.542−0.939) 0.016

OS, Overall Survival.