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. 2021 Mar 3;13(5):7454–7464. doi: 10.18632/aging.202610

Table 2. Prediction of stroke severity and functional outcome.

Parameter AUC 95% CI p
Prediction of high clinical severity
Gal-3 0.72 0.66 0.76 <0.001
CRP 0.58 0.52 0.65 0.012
Age 0.56 0.51 0.63 0.038
Combined score (Gal-3+CRP) 0.73 0.67 0.78 <0.01
Prediction of poor outcome
NIHSS 0.76 0.70 0.83 <0.001
Gal-3 0.76 0.70 0.82 <0.001
CRP 0.62 0.55 0.69 0.001
Age 0.60 0.53 0.66 0.010
Combined score (NIHSS+Gal-3) 0.82 0.77 0.87 <0.01

High clinical severity was defined as a NIHSS >5.

Poor functional outcome was defined as a mRS 3-6.

NIHSS, National Institutes of Health Stroke Scale; CRP, C–reactive protein; Gal-3, galectin-3; AUC, area under the curve; CI= confidence interval.