Table 2. Prediction of stroke severity and functional outcome.
Parameter | AUC | 95% CI | p | |
Prediction of high clinical severity† | ||||
Gal-3 | 0.72 | 0.66 | 0.76 | <0.001 |
CRP | 0.58 | 0.52 | 0.65 | 0.012 |
Age | 0.56 | 0.51 | 0.63 | 0.038 |
Combined score (Gal-3+CRP) | 0.73 | 0.67 | 0.78 | <0.01 |
Prediction of poor outcome‡ | ||||
NIHSS | 0.76 | 0.70 | 0.83 | <0.001 |
Gal-3 | 0.76 | 0.70 | 0.82 | <0.001 |
CRP | 0.62 | 0.55 | 0.69 | 0.001 |
Age | 0.60 | 0.53 | 0.66 | 0.010 |
Combined score (NIHSS+Gal-3) | 0.82 | 0.77 | 0.87 | <0.01 |
†High clinical severity was defined as a NIHSS >5.
‡Poor functional outcome was defined as a mRS 3-6.
NIHSS, National Institutes of Health Stroke Scale; CRP, C–reactive protein; Gal-3, galectin-3; AUC, area under the curve; CI= confidence interval.