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. 2021 Mar 3;13(5):7454–7464. doi: 10.18632/aging.202610

Table 3. Multivariate analysis of predictors of poor functional outcome..

Factors OR (95%CI) P
Gal-3 ≥11.6 ng/ml 3.15(2.44-3.87) <0.001
CRP (increase per unit) 1.05(1.02-1.09) 0.011
Age (increase per unit) 1.07(1.03-1.11) 0.002
NIHSS (increase per unit) 1.22(1.13-1.30) <0.001
Acute treatment (Yes vs. no) 0.25(0.15-0.30) <0.001
Stroke subtype (Large artery vs. others) 2.45(1.56-3.31) 0.040

Multivariable model included the following variables: demographic characteristics, clinical findings at admission, vascular risk factors, NIHSS at admission, stroke subtype, acute stroke treatment and serum levels of CRP, FSG and Gal-3. Poor functional outcome was defined as an mRS 3-6.

The lowest three quartiles(Q1-3) as the reference(<11.6ng/ml).

OR, odds ratio; CI, confidence interval; NIHSS, National Institutes of Health Stroke Scale; CRP, C–reactive protein; mRS, modified Rankin Scale; FSG, fasting serum glucose; BMI, body mass index; Gal-3, galectin-3