Table 3. Multivariate analysis of predictors of poor functional outcome.‡.
Factors | OR (95%CI) | P |
Gal-3 ≥11.6 ng/ml† | 3.15(2.44-3.87) | <0.001 |
CRP (increase per unit) | 1.05(1.02-1.09) | 0.011 |
Age (increase per unit) | 1.07(1.03-1.11) | 0.002 |
NIHSS (increase per unit) | 1.22(1.13-1.30) | <0.001 |
Acute treatment (Yes vs. no) | 0.25(0.15-0.30) | <0.001 |
Stroke subtype (Large artery vs. others) | 2.45(1.56-3.31) | 0.040 |
‡ Multivariable model included the following variables: demographic characteristics, clinical findings at admission, vascular risk factors, NIHSS at admission, stroke subtype, acute stroke treatment and serum levels of CRP, FSG and Gal-3. Poor functional outcome was defined as an mRS 3-6.
† The lowest three quartiles(Q1-3) as the reference(<11.6ng/ml).
OR, odds ratio; CI, confidence interval; NIHSS, National Institutes of Health Stroke Scale; CRP, C–reactive protein; mRS, modified Rankin Scale; FSG, fasting serum glucose; BMI, body mass index; Gal-3, galectin-3