Table 1. Baseline characteristics and genetic variation according to CYP2C19 variant in elderly patients.
| NM or IM | PM | p-value | |
| (n=694) | (n=117) | ||
| Male sex | 376 (54.2%) | 57 (48.7%) | 0.320 |
| Age (years) | 79.1±3.7 | 79.1±3.4 | 0.835 |
| Body-mass index (kg/m2) | 23.7±3.4 | 23.7±3.1 | 0.978 |
| Current smoker | 71 (10.2%) | 16 (13.7%) | 0.341 |
| Hypertension | 508 (73.2%) | 86 (73.5%) | 1.000 |
| Diabetes mellitus | 242 (34.9%) | 36 (30.8%) | 0.448 |
| Hypercholesterolemia | 211 (30.4%) | 41 (35.0%) | 0.371 |
| Previous MI | 46 (6.6%) | 5 (4.3%) | 0.444 |
| Previous PCI | 106 (15.3%) | 20 (17.1%) | 0.715 |
| Previous CABG | 9 (1.3%) | 2 (1.7%) | 1.000 |
| Previous CVA | 75 (10.8%) | 16 (13.7%) | 0.453 |
| Congestive heart failure | 44 (6.3%) | 8 (6.8%) | 1.000 |
| Chronic kidney disease | 49 (7.1%) | 4 (3.4%) | 0.203 |
| Familial history of CAD | 23 (3.3%) | 5 (4.3%) | 0.801 |
| Anemia | 329 (47.4%) | 53 (45.3%) | 0.692 |
| Presentation with ACS | 382 (55.0%) | 70 (59.8%) | 0.366 |
| PRECISE-DAPT score | 25.9 ± 9.3 | 25.8 ± 10.3 | 0.889 |
| - High risk | 328 (47.3%) | 50 (42.7%) | 0.384 |
| P2Y12 G52T (rs6809699) | 0.238 | ||
| - GG | 519 (74.8%) | 79 (67.5%) | |
| - GT | 153 (22.0%) | 34 (29.1%) | |
| - TT | 22 (3.2%) | 4 (3.4%) |
Values are expressed as the number of patients (%) or mean (SD). ACS, acute coronary syndrome; CABG, coronary artery bypass graft; CAD, coronary artery disease; CVA, cerebrovascular accident; IM, intermediate metabolizer; MI, myocardial infarction; NM, normal metabolizer; PCI, percutaneous coronary intervention; PM, poor metabolizer.