Table 3. Characteristics of the 12 centenarians.
| Characteristics |
Survivors (n=6) |
Deceased (n=6) |
| Age (years) | ||
| 100 | 3 | 2 |
| 101-105 | 3 | 4 |
| Gender | ||
| Men | 0 | 1 |
| Women | 6 | 5 |
| Flu Vaccination | 3 | 6 |
| Comorbidities | ||
| Cognitive impairment * | 5 | 5 |
| Hypertension | 2 | 4 |
| Atrial fibrillation | 2 | 1 |
| Cardiac deficiency | 2 | 0 |
| Diabetes | 0 | 1 |
| Cerebrovascular disease | 2 | 0 |
| Cancer history | 0 | 2 |
| Renal chronic disease | 2 | 2 |
| Depression | 4 | 3 |
| Iso-resource group (n=11) | ||
| 1 | 1 | 3 |
| 2 and more | 4 | 3 |
| Nutritional status (n=9) ** | ||
| BMI <21 kg/m2 | 4 | 3 |
| BMI <18 kg/m2 | 0 | 2 |
| BMI ≥30 kg/m2 | 0 | 1 |
| Polypharmacy (≥ 5 drugs) | 3 | 1 |
| Asymptomatic | 2 | 0 |
| Symptoms | ||
| Dyspnea | 2 | 2 |
| Dry cough | 1 | 1 |
| Fever | 3 | 3 |
| Hypothermia | 0 | 1 |
| Asthenia | 4 | 2 |
| Anorexia | 2 | 3 |
| Gastrointestinal signs | 1 | 1 |
| Ear, Nose, Throat (ENT) | 2 | 0 |
| Delirium | 1 | 1 |
| Depression worsening | 1 | 2 |
| Treatment | ||
| Antibiotics *** | 4 | 6 |
| Azithromycin | 5 | 5 |
| Hydroxychloroquine | 0 | 1 |
| Hydration | 4 | 5 |
| Preventive anticoagulation | 3 | 1 |
| Oxygen therapy | 1 | 4 |
| Drug-drug interactions | 3 | 2 |
| Adverse event | 0 | 1 |
| Biological characteristics (n=9) **** | ||
| Anemia | 3 | 3 |
| Neutropenia | 0 | 1 |
| Lymphopenia | 1 | 3 |
| C-reactive protein >10mg/l | 4 | 3 |
*Cognitive impairment: Mini Mental State Examination score <24 and/or presence of cognitive symptoms and/or cognitive disorders history.
**Malnutrition was defined as body mass index < 21 kg/m2, severe malnutrition as body mass index < 18 kg/m2 and obesity as body mass index ≥30 kg/m2.
***Antibiotics used were penicillin, ceftriaxone, macrolides (other than azithromycin) and tetracycline.
****Anemia was defined as hemoglobin level <120 g/L; Neutropenia as neutrophils level <1.5 G/L; Lymphopenia as lymphocytes level <1.0 G/L; thrombopenia was defined as platelets level < 150 G: L / BMI= body mass index; N= number.