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. 2020 Aug 7;13(5):7660–7675. doi: 10.18632/aging.103564

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Copyright: © 2020 Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Repression of miR-493-5p reverses the impacts of NR2F1-AS1 silencing on NSCLC cells. H460 and A549 cells were transfected with si-NR2F1-AS1 in combination with miR-493-5p inhibitor or NC inhibitor. (A, B) Rescue effects of miR-493-5p inhibition on si-NR2F1-AS1-mediated inhibition of cell growth and promotion of apoptosis in H460 and A549 cells were explored by CCK-8 assay and flow cytometry analysis. (C, D) Rescue effects of miR-493-5p inhibition on si-NR2F1-AS1-mediated suppression of cell migration and invasion in H460 and A549 cells were evaluated by cell migration and invasion assays (x200 magnification). *P < 0.05 and **P < 0.01.