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. 2021 Mar 1;13(5):6359–6374. doi: 10.18632/aging.202715

Table 1. Patient characteristics, laboratory values and medical treatment.

Pediatric patients Adult patients
De novo Previously diagnosed De novo Previously diagnosed
Demographics
Patients (n) 15 15 15 15
Sex (n)
Male 6 5 7 6
Female 9 10 8 9
Median age (IQR) 13 (9-15) 15 (11-16) 29 (25-40) 31 (25-39)
Disease parameters
Phenotype (n)
Remission - 3 - 2
Proctitis 5 4 6 2
Left sided 1 3 4 2
Extensive 9 5 5 9
UCEIS (median (IQR)) 3 (1-6) 1 (0-4) 3 (1-5) 1 (0-4)
Geboes score (n)
0-1 / 2-3 / >3 2 / 9 / 4 6 / 6 / 3 4 / 3 / 8 8 / 5 / 2
Biomarkers (median [IQR])
Fecal calprotectin (μg/g)a 1340 (97-1800) 525 (62-1080) 1800 (1130-1800) 1042 (300-1800)
C-reactive protein (mg/L) 1 (0-9) 1 (0-2) 2 (0-5) 8 (3-22)
Albumin (g/L) 37 (34-40) 38 (36-39) 38 (35-43) 36 (33-40)
Hemoglobin (mmol/L) 7.5 (7.1-8.3) 7.8 (6.9-8.1) 8.6 (8.1-9.5) 8.1 (7.5-8.8)
Erythrocyte sedimentation rate 10.5 (3-16) 6 (4-18) 5 (3-16) 13 (3-21)
Neutrophils (E^9/L) 4 (3-6) 4 (3-4) 4 (4-5) 6 (4-8)
Treatment (n)
Oral 5-aminosalicylic acid - 12 4 10
Topic 5-aminosalicylic acid - 3 3 9
Systemic corticosteroids - 2 - 2
Topical corticosteroids - 1 - 1
Thiopurines - 7 - 4
Biologics - 6 - 1

Due to laboratory restrictions fecal calprotectin was capped at 1800 μg/g. IQR, Interquartile range. N, number. UCEIS, Ulcerative Colitis Endoscopic Index of Severity.