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. 2021 Mar 25;16(3):e0248241. doi: 10.1371/journal.pone.0248241

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© 2021 Shrestha et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) Hierarchical cluster analysis and heat map of correlation; (B) Principal component analysis (PCA), between the replicates and different concentration using gene expression dataset. (C) ANOVA and post-hoc analysis test results. Red and green point represents the probes with below and above adjusted p-value (FDR) cutoff 0.05. X axis represents number of genes; Y axis represents negative adjusted p-value (FDR). Boxplots of top four probes (genes) are shown as an example to demonstrate the outcome variation, where X axis represents different concentrations; Y axis represents probe (gene) expression.