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. 2021 Mar 25;16(3):e0248241. doi: 10.1371/journal.pone.0248241

Table 2. mTOR and associated genes identified by global gene expression.

Gene Symbol Gene Name Global Gene Expression
Induced (I) Repressed (R)
FRAP1 mammalian target of rapamycin (mTOR) R (0.66)
FKBP2 FKBP prolyl isomerase 2 I (1.24, 16mM) R (0.95, 7.5 mM)
FKBP11 FKBP prolyl isomerase 11 R (0.47)
TSC1 TSC complex subunit 1 R (0.73)
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 R (0.67)
FNIP1 folliculin interacting protein 1 R (0.67)
OGT O-linked N-acetylglucosamine transferase 2 R (0.55)
SKP2 S-phase kinase-associated protein 2 I (1.22, 16 mM)
RNF152 E3 ubiquitin-protein ligase R (0.85)
CREB3L2 cyclic AMP-responsive element-binding protein 3-like protein 2 R (0.66)
RAPTOR regulatory associated protein of MTOR complex 1 R (0.76)
RICTOR independent companion of MTOR complex 2 R (0.71)
DEPTOR domain containing MTOR interacting protein R (0.69)
MLST8 MTOR associated protein R (0.75)
RHEB Ras homolog, MTORC1 binding R (0.80)