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. 2021 Mar 25;16(3):e0249240. doi: 10.1371/journal.pone.0249240

Fig 4. Associations of allopurinol with renal and non-renal outcomes.

Fig 4

CI, confidence interval; HR, hazard ratio; PRD, primary renal disease; HTN, hypertensive renal disease; DN, diabetic nephropathy; CVEs, cardio-vascular events. †Associations are measured per 1 mg/dl increment of UA using Cox proportional hazard regression. Hazard ratios (HRs) were adjusted for underlying disease of CKD, eGFR, urinary protein, systolic blood pressure, past history of cardiac disease, ACEi/ARBs, diuretics, statins, antiplatelets, allopurinol, age, sex, smoking, body mass index, hemoglobin, albumin.