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Chemical structures of PEG. a Commonly used PEG architectures and functionalization. R represents a functional group. b Common PEG R groups: i malemide; ii succinimidyl succinate; iii vinyl sulfone; iv N-hydroxysuccinimide. c Click chemistry reaction between a bifunctional PEG chain and amine group on a protein coated surface. d PEGylated lipid, mPEG-DSPE, used in the formulation of PEGylated liposomal drugs such as Doxil®
