Table-1.
Fecal egg count reduction test and lower limits of 95% confidence level calculated on the basis of individual animal’s egg counts before and after treatment on the same sheep using method of Kochapakdee et al. [27]. FECRT%=100 × (1−(T2/T1).
| Study site | Anthelmintic used | FEC1 (Range) | FEC2 (Range) | FECRT% | Lower limit of 95% confidence | Interpretation of results |
|---|---|---|---|---|---|---|
| Sekh | BZ | 1940 (1455-2425) | 80 (60-100) | 96 | 93 | Suspected resistance |
| LEV | 2080 (1560-2600) | 150 (112-187) | 94 | 90 | Suspected resistance | |
| ML | 2030 (1522-2537) | 120 (90-150) | 96 | 90 | Suspected resistance | |
| Control | 2080 (1560-2200) | 2060 (1840-2560) | - | - | - | |
| Capr | BZ | 1790 (895-3580) | 200 (100-400) | 92 | 85 | Resistant |
| LEV | 1660 (830-3320) | 130 (65-260) | 93 | 88 | Resistant | |
| ML | 1840 (920-3680) | 120 (60-240) | 92 | 90 | Suspected resistance | |
| Control | 1750 (1430-2080) | 1940 (1850-2300) | - | - | - | |
| W/berg | BZ | 2840 (2200-3500) | 1300 (400-2300) | 56 | 40 | Resistant |
| LEV | 2960 (1300-5000) | 580 (200-900) | 79 | 72 | Resistant | |
| ML | 4440 (2200-7200) | 1340 (0-2000) | 65 | 50 | Resistant | |
| Control | 1570 (1410-1600) | 1580 (1380-1670) | - | - | - | |
| Mopani | BZ | 1960 (500-5000) | 620 (300-880) | 47 | 26 | Resistant |
| LEV | 1620 (400-2300) | 480 (100-900) | 70 | 61 | Resistant | |
| ML | 1280 (500-2400) | 320 (100-900) | 72 | 51 | Resistant | |
| Control | 1180 (850-1250) | 1180 (900-1250) | - | - | - | |
| Vhembe | BZ | 2660 (500-4400) | 340 (0-1000) | 89 | 82 | Resistant |
| LEV | 2525 (400-7800) | 50 (0-500) | 90 | 78 | Suspected resistance | |
| ML | 1060 (500-2000) | 160 (0-300) | 90 | 80 | Resistant | |
| Control | 1290 (1100-1350) | 1280 (1080-1580) | - | - | - |
Sekh=Sekhukhune, Capr=Capricorn, W/berg=Waterberg, BZ=Benzimidazole (Valbazen®), LEV=Levamisole (Tramisol Ultra®), ML=Macrocyclic lactones (Ivomec®), FEC1=Fecal egg count pre-treatment, FEC2=Fecal egg count 14 days post-treatment