Table-3.
Biochemical parameters of mice serum after acute oral administration of extracts of the different parts of the two varieties studied.
| Simples code | Doses mg/kg | Biochemical parameters | ||||
|---|---|---|---|---|---|---|
| AST | ALT | Urea | Creatinine | |||
| Anacyclus Pyrethrum var. Pyrethrum | Roots (APPR) | 300 | 250±6.65*** | 30.33±1.33 | 0.28±0.007 | 4.23±0.14 |
| 500 | 261±4.05** | 31±2.02 | 0.38±0.012 | 4±0.208 | ||
| 2000 | 315±14** | 54±4.04 | 0.37±0.02 | 4.5±0.28 | ||
| Seeds (APPG) | 300 | 285.66±8.17 | 32±2.9 | 0.37±0.01 | 3.5±0.28 | |
| 500 | 257.7±4.05** | 40.35±3.52 | 0.3±0.03 | 3.56±0.29 | ||
| 2000 | 210±9.07*** | 50.7±1.85 | 0.40±0.06 | 4.23±0.62 | ||
| Leaves (APPF) | 300 | 277±4.93 | 36.6±4.09 | 0.29±0.04 | 3.93±0.43 | |
| 500 | 275±4.63 | 30±0.57 | 0.35±0.01 | 3.46±0.08 | ||
| 2000 | 232±5.92*** | 39±3.17 | 0.40±0.04 | 3.54±0.29 | ||
| Capitulas (APPC) | 300 | 286.33±8.08 | 42.53±2.02 | 0.38±0.01 | 3.73±0.17 | |
| 500 | 258.7±3.28** | 36±1.52 | 0.31±0.03 | 3.63±0.27 | ||
| 2000 | 296±6.48 | 32±6.11 | 0.32±0.01 | 3.5±0.28 | ||
| Anacyclus Pyrethrum var. Depressus | Roots (APDR) | 300 | 255±5.78** | 31.55±3.71 | 0.28±0.17 | 4±0.57 |
| 500 | 254.3±3.52** | 32±2.08 | 0.42±0.01 | 3.43±0.14 | ||
| 2000 | 326±15.37*** | 63±7.21* | 0.48±0.05 | 4.23±0.39 | ||
| Seeds (APDG) | 300 | 285±9.84 | 41.66±1.76 | 0.31±0.01 | 4.06±0.12 | |
| 500 | 258±2.64** | 33.8±2.4 | 0.28±0.03 | 4±0.12 | ||
| 2000 | 234±12.41*** | 26.4±3,71 | 0.44±0.02 | 3.4±0.33 | ||
| Leaves (APDF) | 300 | 281.3±8.76 | 30.33±3.52 | 0.30±0.03 | 4.33±0.33 | |
| 500 | 272±4.37 | 31±0,88 | 0.31±0.02 | 3.36±0.20 | ||
| 2000 | 254.7±10.89* | 50.6±8.29 | 0.42±0.04 | 3.96±0.54 | ||
| Capitulas (APDC) | 300 | 275.23±13.1 | 35±2.02 | 0.41±0.009 | 3±0.23 | |
| 500 | 260±4.80** | 35.37±5.04 | 0.29±0.017 | 3.53±0.29 | ||
| 2000 | 235±11.71*** | 48±6.55 | 0.52±0.08 | 5±0.57 | ||
| Control | Physiological water | 278±4.35 | 39±1.73 | 0.30±0.01 | 3.6±0.32 | |
Values are expressed mean±SEM. AST=Aspartate aminotransferase, ALT=Alanine aminotransferase.
Correlation is significant at the level P<0.05.
Correlation is significant at the level P<0.01
Correlation is significant at the level P<0.001. Values are expressed mean±SEM. APPR=Anacyclus pyrethrum var. pyrethrum roots, APPG=Anacyclus pyrethrum var. pyrethrum seeds, APPF=Anacyclus pyrethrum var. pyrethrum leaves, APPC=Anacyclus pyrethrum var. pyrethrum capitula, APDR=Anacyclus pyrethrum var. depressus roots, APDG=Anacyclus pyrethrum var. depressus seeds, APDF=Anacyclus pyrethrum var. depressus leaves, APDC=Anacyclus pyrethrum var. depressus capitula