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. 2021 Mar 1;11(3):712–728.

Figure 7.

Figure 7

FSTL1 can promote the activation of AKT by regulating TLR4/CD14. A. Correlation analysis between TLR4/CD14/Follistatin/DIP2A expression and FSTL1 level in TCGA database. B. The physical interaction between TLR4, CD14, Follistatin, DIP2A and FSTL1 in SGC7901, HGC27 and BGC823 cells by co-immunoprecipitation. C. Correlation analysis between TLR4, CD14 mRNA expression and FSTL1 mRNA level in 30 fresh frozen GC tissues. D. Correlation analysis between TLR4, CD14 expression and FSTL1 level in 10 freshly GC tissues. E. Immunofluorescence images of TLR4, CD14, FSTL1 expression in SGC7901 cells. F, G. The protein expression levels of p-AKT, AKT proteins in BGC823 cells after overexpressed FSTL1 or the presence of recombinant FSTL1 and MK2206. A, C, D. Based on Spearman’s rank correlation test.