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. 2021 Mar 1;11(3):640–667.

Table 2.

Stability of the established cell lines

Periods IC50/(µg/ml) Resistance Index, RI IC50/(µg/ml) Resistance Index, RI


HNE-1 HNE-1/DDP CNE-2 CNE-2/DDP
Established 0.594 7.08 11.92 0.453 21.341 47.11
3 months without CDDP - 5.979 10.07 - 16.717 36.90
6 months’ storage in liquid nitrogen 0.679 8.26 12.16 0.459 20.252 44.12