Table 3.
Partial correlations between blood counts, blood count ratios, inflammatory markers, and creatinine and HE4 and CA125, stratified by menopausal status.
| All | Premenopausal | Postmenopausal | ||||
|---|---|---|---|---|---|---|
| HE41 r (p)2 |
CA1251 r (p)3 |
HE41 r (p)2 |
CA1251 r (p)3 |
HE41 r (p)2 |
CA1251 r (p)3 |
|
| Lymphocytes | −0.05 (0.009) | −0.04 (0.04) | −0.04 (0.11) | −0.04 (0.16) | −0.07 (0.03) | −0.01 (0.87) |
| Neutrophils | 0.07 (0.001) | 0.10 (<0.0001) | 0.03 (0.37) | 0.09 (0.001) | 0.13 (<0.0001) | 0.08 (0.008) |
| Monocytes | 0.04 (0.03) | 0.07 (0.001) | −0.01 (0.73) | 0.05 (0.07) | 0.12 (0.0001) | 0.06 (0.04) |
| Hemoglobin | −0.05 (0.03) | −0.07 (0.0009) | −0.02 (0.50) | −0.06 (0.02) | −0.09 (0.006) | 0.00 (0.97) |
| Platelets | 0.01 (0.60) | 0.05 (0.03) | 0.00 (0.92) | 0.01 (0.82) | 0.02 (0.48) | 0.10 (0.001) |
| PNR | −0.06 (0.006) | −0.07 (0.0006) | −0.02 (0.40) | −0.08 (0.006) | −0.11 (0.0006) | −0.02 (0.54) |
| PLR | 0.05 (0.01) | 0.06 (0.003) | 0.04 (0.19) | 0.04 (0.20) | 0.07 (0.03) | 0.06 (0.05) |
| PMR | −0.03 (0.12) | −0.03 (0.10) | 0.01 (0.82) | −0.04 (0.16) | −0.09 (0.005) | 0.01 (0.87) |
| NLR | 0.09 (<0.0001) | 0.12 (<0.0001) | 0.05 (0.08) | 0.10 (0.0002) | 0.15 (<0.0001) | 0.07 (0.02) |
| NMR | 0.03 (0.12) | 0.05 (0.02) | 0.04 (0.21) | 0.05 (0.08) | 0.02 (0.43) | 0.03 (0.39) |
| LMR | −0.08 (<0.0001) | −0.10 (<0.0001) | −0.03 (0.37) | −0.08 (0.008) | −0.16 (<0.0001) | −0.06 (0.06) |
| CRP (mg/dL) | 0.03 (0.20) | 0.07 (0.0003) | −0.03 (0.26) | 0.06 (0.02) | 0.12 (<0.0001) | 0.13 (<0.0001) |
| Homocysteine (umol/L)4 | 0.19 (<0.0001) | −0.02 (0.25) | 0.09 (0.0007) | −0.09 (0.002) | 0.32 (<0.0001) | 0.06 (0.04) |
| Creatinine (mg/dL)4 | 0.25 (<0.0001) | 0.02 (0.46) | 0.12 (<0.0001) | −0.05 (0.06) | 0.42 (<0.0001) | 0.08 (0.009) |
Partial correlation between HE4 and CA125 adjusted for age (continuous), age-squared (continuous), race/ethnicity (Mexican American, other Hispanic, non-Hispanic white, non-Hispanic Black, and other races), BMI (<18.5, 18.5–24.9, 25–29.9, 30–34.9, 35–39.9, and ≥40 kg/m2), and smoking status (never, former, current): all r=0.02 (p=0.29); premenopausal r=−0.02 (p=0.37); postmenopausal r=0.10 (p=0.002).
Adjusted for age (continuous), age-squared (continuous), and smoking status (never, former, current)
Adjusted for age (continuous), race/ethnicity (Mexican American, other Hispanic, non-Hispanic white, non-Hispanic Black, and other races), and BMI (<18.5, 18.5–24.9, 25–29.9, 30–34.9, 35–39.9, and ≥40 kg/m2)
Partial correlation between homocysteine and creatinine adjusted for age (continuous): all r=0.48 (p<0.0001); premenopausal r=0.48 (p<0.0001); postmenopausal r=0.49 (p<0.0001).