Table 2:
Hazard ratios by TP53 mutational status on bevacizumab-containing arms (Arms 1 and 3) vs. the temsirolimus-containing arm (Arm 2).
| Endpoint | Group | Point Estimate | 95% Profile Likelihood Confidence Limits | |
|---|---|---|---|---|
| PFS | WT | 0.87 | 0.58 | 1.31 |
| Mutant | 0.48 * | 0.31 | 0.75 | |
| OS | WT | 1.05 | 0.64 | 1.77 |
| Mutant | 0.61 * | 0.38 | 0.98 | |
The number of patients in each arm and number events are provided in Supplementary Table I.
denotes statistically significant differences between groups; Arm 2 is the reference arm. WT: wild type TP53; mutant: mutation in TP53.