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. 2021 Mar 2;44(4):479–497. doi: 10.1007/s40264-021-01060-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 3 — Calibrated hazard ratios and calibrated 95% confidence intervals (CIs) for each pairwise comparison during primary and sensitivity observation periods in the venous thromboembolism (VTE) population after 1:1 propensity score matching: (a) rivaroxaban vs warfarin; (b) apixaban vs warfarin; and (c) rivaroxaban vs apixaban. Estimates are reported for pairwise comparisons in databases where study diagnostic passed. Note that limited exposures precluded producing estimates for comparisons including dabigatran in the VTE population. Summary meta-analytic estimates are reported where I² < 40%. CCAE IBM MarketScan^® Commercial Database, cHR calibrated hazard ratio, ITT intent-to-treat, MDCD IBM MarketScan^® Multi-state Medicaid, MDCR IBM MarketScan^® Medicare Supplemental Beneficiaries