Table.
Baseline characteristics of participants included in the analyses (n=938 558)*, by level of social isolation and first coronary heart disease and stroke event
| Least isolated (n=379 031) | Moderately isolated (n=429 541) | Most isolated (n=129 986) | ||
|---|---|---|---|---|
| Baseline characteristics | ||||
| Age at baseline, years | 62·0 (8·6) | 63·3 (8·7) | 62·8 (9·4) | |
| Sex | ||||
| Men | 88 582 (23·4%) | 80 734 (18·8%) | 32 004 (24·6%) | |
| Women | 290 449 (76·6%) | 348 807 (81·2%) | 97 982 (75·4%) | |
| Most deprived quintile† | 45 108 (12·0%) | 73 944 (17·3%) | 33 232 (25·7%) | |
| Current smoker | 19 531 (5·2%) | 35 714 (8·4%) | 17 583 (13·8%) | |
| Obesity (BMI ≥30 kg/m2) | 73 819 (19·7%) | 97 506 (23·2%) | 32 191 (25·4%) | |
| ≥7 units of alcohol per week | 135 279 (38·7%) | 123 681 (32·3%) | 32 923 (29·2%) | |
| Rarely or never exercise | 28 446 (7·9%) | 51 600 (13·3%) | 21 762 (18·8%) | |
| Poor or fair self-rated health | 57 948 (15·4%) | 92 539 (21·7%) | 38 143 (29·6%) | |
| Follow-up for first coronary heart disease event | ||||
| Follow-up duration, years per participant | 7·2 (1·5) | 7·0 (1·6) | 7·0 (1·7) | |
| Person-years, 1000s | 2737 | 3000 | 908 | |
| Number of first events | 15 190 | 19 919 | 7293 | |
| Number of hospital admissions as first event | 14 714 | 19 067 | 6787 | |
| Number of deaths without an associated hospital admission as first event | 476 | 852 | 506 | |
| Follow-up for first stroke event | ||||
| Follow-up duration, years per participant | 7·3 (1·4) | 7·1 (1·5) | 7·1 (1·6) | |
| Person-years, 1000s | 2769 | 3036 | 920 | |
| Number of first events | 6513 | 9748 | 3738 | |
| Number of hospital admissions as first event | 6380 | 9490 | 3600 | |
| Number of deaths without an associated hospital admission as first event | 133 | 258 | 138 | |
Data are mean (SD), n, or n (%). BMI=body-mass index.
*
Data for Million Women Study and UK Biobank participants were combined; baseline characteristics of participants included in each study separately are shown in the appendix (p 4).
†
According to the Townsend Index.14