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Pathway enrichment of metabolites in metabolome fingerprint. A typical feature is that a series of metabolites related to long-chain fatty acids (e.g., 12,13-DHOME, trans-2-Enoyl-OPC4-CoA and Docosadienoyl-CoA, etc.) are significantly reduced. And, a key feature of decompensated liver cirrhosis was observed to be used as energy supply by proteolysis (incomplete breakdown products of protein catabolism increased significantly in DC group).
