FIGURE 1.

Mean clinical scores (A) and survival curves (B) of mice inoculated with each of the seven Vibrio parahaemolyticus strains at a dose of 10⁸ CFU/animal. Eleven clinical signs were evaluated every 24 h for 120 h post-infection, in groups of n = 10 animals per dose of each strain. Control group: mice inoculated with LB medium, n = 5 animals. Strains were grouped according to virulence: group I (green) – high; group II (yellow) – intermediate; and group III (red) – low. Survival curves of mice in each group were generated using the Kaplan–Meier method (Kaplan and Meier, 1958) and compared using the log-rank test (Mantel, 1966; Peto and Peto, 1972), with p-values < 0.05 considered statistically significant.