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. 2021 Mar 23;4(6):e202000903. doi: 10.26508/lsa.202000903

Figure S4. Cancer cells release different set of cytokines depending on the extracellular citrate availability.

Figure S4.

(A, B, C, D, E, F, G, H) The graphs show selected cytokines released from cancer cells grown for 48 h (A, B) or 2 wk (E, D) under the following conditions (A) and preincubated without (CM PC-3M−cit) or (B) with extracellular citrate (CM PC-3M+cit) and fibroblasts (C, D and G, H) transformed by the differentially treated cancer cells (C, G) CM F-PC−cit and (D) CM F-PC+cit (F, H) over 48 h or 2 wk, respectively. (A, B, D, E) The values of cytokines released by fibroblasts were obtained by subtracting the values of cytokines measured in conditioned media from cancer cells (A, B and E, D) from the values measured in the media from fibroblasts.