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Comparison of genes regulated by T3 and specifically by T3+T4. (A) qPCR validation of some genes showing synergistic regulation by T3 and T4. (B) Heat map of the 535 genes significantly regulated by T3. (C) Heat map of 535 genes most significantly and specifically regulated by T3+T4. “abc” indicate p < 0.05 triples+T3+T4 vs. triples, triples+T4, and triples+T3, respectively, as determined by ANOVA and Fisher's LSD test. Dotted lines indicated control values (D1/D2KOPax8Het).
