Table 5.
Comparison of oxidative stress biomarkers of SLE patients with and without disease damage
| Oxidative stress biomarker | SLE disease damage absent (SDI 0) N = 44 | SLE disease damage present (SDI ≥ 1) N = 36 | Statistical significance p value |
|---|---|---|---|
| OxLDL (ng/L) |
2202.86 (502.7–28751.8) |
3687.17 (670.9–28649.7) |
0.03 |
| MDA (μM) |
2.36 (0.83–7.90) |
2.28 (1.03–7.61) |
0.85 |
| 8-OHdG (ng/mL) |
19.06 (0.00–538.77) |
20.39 (0.00–724.52) |
0.10 |
| TAS (units/mL) | 13.15 (4.70) | 11.44 (6.54) | 0.2 |
| MDA/TAS |
0.18 (0.05–7.89) |
0.23 (0.06–7.60) |
0.41 |
All values are median (IQR)
OxLDL Oxidised LDL, MDA Malondialdehyde, 8-OHdG 8-hydroxy-2′-deoxyguanosine, TAS total antioxidant status, SDI SLE damage index