Table 6.
Comparison of OxLDL, 8-OHdG, MDA, total antioxidant status, MDA/TAS in relation to autoantibody status
| Autoantibody positive | Autoantibody negative | p | |
|---|---|---|---|
| OxLDL* | |||
|
SSA (N = 53) OxLDL |
23 2207.46 (503–17665) |
30 2167.00 (905–28752) |
0.733 |
|
SSB (N = 53) OxLDL |
7 2586.55 (1192–17665) |
46 2166.68 (503–28752) |
0.813 |
|
Sm (N = 53) OxLDL |
15 1797.63 (503–17703) |
38 2253.28 (906–28752) |
0.236 |
|
Nucleosome (N = 53) OxLDL |
23 2119.42 (503–17703) |
30 2253.28 (905–28752) |
0.720 |
|
ds-DNA (N = 66) OxLDL |
47 2785.06 (503–28650) |
19 2119.42 (671–27103) |
0.388 |
| 8-OHdG* | |||
|
SSA (N = 53) 8-OHdG |
23 17.57 (0–241) |
30 18.73 (13–344) |
0.518 |
|
SSB (N = 53) 8-OHdG |
7 19.6 (13–241) |
46 18.56 (0–344) |
0.563 |
|
Sm (N = 53) 8-OHdG |
15 17.51 (0–344) |
38 18.64 (0–304) |
0.441 |
|
Nucleosome (N = 53) 8-OHdG |
23 19.6 (0–344) |
30 18.43 (0–304) |
0.647 |
|
ds—DNA (N = 66) 8-OHdG |
47 19.60 (0–725) |
19 18.79 (16–142) |
0.804 |
| MDA* | |||
|
SSA (N = 53) MDA |
23 2.49 (1–8) |
30 2.21 (1–8) |
0.49 |
|
SSB (N = 53) MDA |
7 3.08 (2–8) |
46 2.23 (1–8) |
0.134 |
|
Sm (N = 53) MDA |
15 2.23 (1–8) |
38 2.41 (1–8) |
0.790 |
|
Nucleosome (N = 53) MDA |
23 2.23 (1–8) |
30 2.41 (1–8) |
0.936 |
|
ds-DNA (N = 66) MDA |
47 2.53 (1–8) |
19 1.93 (1–5) |
0.003 |
| TAS* | |||
|
SSA (N = 53) TAS |
23 14.48 (0–18) |
30 13.30 (0–18) |
0.666 |
|
SSB (N = 53) TAS |
7 7.10 (0–15) |
46 14.36 (0–18) |
0.012 |
|
Sm (N = 53) TAS |
15 13.23 (0–18) |
38 14.42 (0–18) |
0.244 |
|
Nucleosome (N = 53) TAS |
23 14.35 (0–18) |
30 13.30 (0–18) |
0.986 |
|
ds-DNA (N = 66) TAS |
47 12.9 (0–18) |
19 17.22 (0–18) |
0.004 |
| MDA/TAS* | |||
|
SSA (N = 53) MDA/TAS |
23 0.20 (0.05–7.89) |
30 0.22 (0.05–4.75) |
0.97 |
|
SSB (N = 53) MDA/TAS |
7 0.43 (0.14–7.60) |
46 0.17 (0.05–7.8) |
0.026 |
|
Sm (N = 53) MDA/TAS |
15 0.17 (0.05–7.89) |
38 0.21 (0.05–7.60) |
0.95 |
|
Nucleosome (N = 53) MDA/TAS |
23 0.17 (0.06–4.75) |
30 0.24 (0.05–7.89) |
0.97 |
|
ds-DNA (N = 66) MDA/TAS |
47 0.27 (0.05–7.89) |
19 0.12 (0.05–2.24) |
0.06 |
OxLDL oxidised LDL, 8-OHdG 8-hydroxy-2′-deoxyguanosine, MDA malonaldehyde, TAS total antioxidant status
Units of measurements—OxLDL is in ng/L, 8-OHdG is ng/ml, MDA is μM, TAS is U/mL
*All values are median (IQR)