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. 2021 Mar 12;11:646141. doi: 10.3389/fonc.2021.646141

Table 2.

Association of FDG-PET/CT parameters with clinicopathological parameters.

SUVmax MTV3.5 TLG3.5
mean ± SD R2 P mean ± SD R2 P mean ± SD R2 P
Sex 0.115 0.161 0.141
 Male 4.75 ± 1.60 3.11 ± 4.68 13.71 ± 20.98
 Female 5.49 ± 2.06 4.98 ± 6.50 22.03 ± 26.00
Age 0.03 0.135 <0.001 0.808 <0.001 0.985
Pre-treatment CA19-9 0.011 0.380 0.039 0.093 0.048 0.063
Resectability 0.0379* 0.0125* 0.0096
 R 4.74 ± 1.59 2.68 ± 3.67 11.84 ± 16.53
 BR 5.66 ± 2.04 6.02 ± 7.51 26.53 ± 30.74
Tumor size 0.051 0.053 0.2562 <0.0001§ 0.273 <0.0001§
Differentiation 0.333 0.7130 0.6944
 Well 4.43 ± 1.54 4.29 ± 4.97 16.45 ± 29.40
 Mod 5.24 ± 1.83 4.01 ± 4.97 18.25 ± 22.81
 Poor 4.83 ± 1.97 1.88 ± 2.25 8.62 ± 11.75
pT 0.077 0.1820 0.1102
 2 4.07 ± 1.99 2.15 ± 3.03 9.06 ± 12.81
 3 4.72 ± 1.70 2.91 ± 5.28 12.51 ± 20.94
 4 5.64 ± 1.80 5.30 ± 5.60 24.03 ± 25.53
LN metastasis 0.0437* 0.6441 0.4716
 Yes 5.61 ± 1.89 3.55 ± 6.00 15.21 ± 24.46
 No 4.73 ± 1.67 4.17 ± 4.31 19.31 ± 20.50

Data are expressed as mean ± SD (range) or number of patients.

*P < 0.05; P < 0.01; §P < 0.001.

BR, borderline resectable; CA19-9, cancer antigen 19-9; LN, lymph node; MTV, mean tumor volume; R, resectable; SD, standard deviation; SUVmax, maximum standardized uptake value; TLG, total lesion glycolysis.