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. 2021 Mar 12;11:646141. doi: 10.3389/fonc.2021.646141

Table 5.

Multivariate analysis with SUVmax, MTV3.5, and TLG3.5 for RFS.

RFS model with SUVmax RFS model with MTV3.5 RFS model with TLG3.5
P Hazard ratio 95% CI P Hazard ratio 95% CI P Hazard ratio 95% CI
Sex 0.267 1.386 0.778–2.467 0.230 1.425 0.800–2.539 0.331 1.327 0.750–2.349
Age ≥66 0.282 1.421 0.749–2.695 0.366 1.340 0.711–2.526 0.380 1.329 0.704–2.510
CA19-9 ≥276.5 0.058 1.748 0.982–3.112 0.040* 1.829 1.030–3.250 0.060 1.936 0.978–3.084
Resectability, BR 0.098 1.651 0.912–2.988 0.219 1.435 0.807–2.553 0.187 1.473 0.187–0.828
SUVmax ≥4.87 0.041* 1.797 1.026–3.149
MTV3.5 ≥2.46 0.030* 1.849 1.062–3.220
TLG3.5 ≥9.99 0.128 1.527 0.886–2.632

BR, borderline resectable; CA19-9, cancer antigen 19-9; CI, confidence interval; DSS, disease-specific survival; MTV, mean tumor volume; RFS, recurrence free survival; SD, standard deviation; SUVmax, maximum standardized uptake value; TLG, total lesion glycolysis.

*P < 0.05.