Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A pathway of melatonin biosynthesis. Melatonin synthesis is the result of the amino acid tryptophan through the intermediate neurotransmitter serotonin. The conversion of serotonin to melatonin is mediated by two enzymes, serotonin N-acetyl transferase (SNAT) and acetylserotonin O-methyltransferase (ASMT). The protein 14-3-3 mediates both of these stepwise interactions.
