Table 2.

Detailed clinical features of patients at baseline and at 3- and 6-month follow-ups.

Patient	Baseline				3-month follow-up				6-month follow-up
	Deep tendon reflexes	Sensory symptoms and signs	MRC scale Upper limbs: R/L	MRC scale Lower limbs: R/L	Deep tendon reflexes	Sensory symptoms and signs	MRC scale Upper limbs: R/L	MRC scale Lower limbs: R/L	Deep tendon reflexes	Sensory symptoms and signs	MRC scale Upper limbs: R/L	MRC scale Lower limbs: R/L
#1	Absent in the lower and upper limbs, normal plantar reflex response bilaterally	Severe hypoesthesia in the lower limbs till the superior anterior iliac spine	39/35	19/21	Hyporeflexia only in the lower limbs, normal plantar reflex response bilaterally	Moderate hypoesthesia at the lower limbs	24/24	9/9	Areflexia of the Achilles reflexes; DPR normalized in the other districts; normal plantar reflex response bilaterally	Mild hypoesthesia in the lower limbs, till the ankle	42/41	18/18
#2	Hyporeflexia in the upper limbs, areflexia in the lower limbs, silent plantar reflex response bilaterally	Distal hypoesthesia and paresthesia in the four limbs	21/23	6/8	Hyporeflexia in the upper limbs, areflexia in the lower limbs, silent plantar reflex response bilaterally	Slight improvement of the distal hypoesthesia and paresthesia in the four limbs	22/24	6/9	Hyporeflexia in the lower limbs, abnormal plantar reflex response bilaterally	Mild distal paraesthesia in the lower limbs	28/29	13/14
#3	Hyporeflexia of the patellar reflexes, areflexia of the Achilles tendon reflexes, silent plantar reflex response bilaterally	Distal hypoesthesia in the four limbs more prominent in the right lower limb below the knee; distal apallesthesia in the lower limbs	41/41	12/25	Areflexia of the Achilles reflexes, silent plantar reflex response bilaterally	Mild recovery of the hypoesthesia now confined to the right lower limb above the knee and at the left foot; no variation in the distal apallesthesia in the lower limbs	42/38	17/19	NA	NA	NA	NA
#4	Hyporeflexia in the upper limbs, areflexia in the lower limbs, bilateral Babinski sign	Severe hypoesthesia and hypopallesthesia in the lower limbs	40/40	9/6	Hyperreflexia in the lower limbs, bilateral Babinski sign	Mild hypoesthesia in the lower limbs	40/40	21/20	Mild hyperreflexia at lower limbs, bilateral Babinski sign	Normal	40/40	24/24
#5	Hyperreflexia of the patellar and Achilles tendon reflexes, bilateral Babinski sign	Severe hypoesthesia and hypopallesthesia in the lower part of the body with upper level at T4-T5	40/40	16/16	Hyperreflexia of the patellar and Achilles reflexes with ankle clonus; bilateral Babinski sign	Moderate improvement of the hypoesthesia, upper level at T4-T5	40/40	19/20	Hyperreflexia of the patellar and Achilles reflexes with ankle clonus; bilateral Babinski sign	Mild hypoesthesia with upper level T4-T5	40/40	24/24

DPR, Deep Tendon Reflexes; MRC, Medical Research Council Scale for muscle strength assessment. Muscle effort evaluated in the upper limbs (sum score ranging between 0 and 40 for each body side) included: deltoid, biceps brachii, triceps brachii, wrist extension, wrist flexion, finger extension, finger flexion, first dorsal interosseous muscles. Muscle effort evaluated in the lower limbs (sum score ranging between 0 and 25 for each body side) included: iliopsoas, quadriceps femoralis, gastrocnemius, tibialis anterior, extensor hallucis longus mucles.