Table 4. Biochemical index.
| Variable | Control | Testosterone treatment | |||
|---|---|---|---|---|---|
| BPH | CO (0.075 mg/kg) | DCL (0.075 mg/kg) | Finasteride (0.8 mg/kg) | ||
| AST (U/L) | 96.0±18.5 | 125.2±46 | 78.3±21.3a | 89.5±9.3 | 80.7±15.3a |
| ALP (U/L) | 91.5±21.8 | 85.7±22.2 | 61.2±12.1 | 77.5±13.7 | 81.5±17.7 |
| Creatinine (mg/dL) | 0.4±0.1 | 0.4±0.1 | 0.3±0.1a | 0.3±0 | 0.3±0.1a |
| Total cholesterol (mg/dL) | 93.3±10.4 | 88.2±11.1 | 79.7±14.9 | 76.8±17.6 | 70.8±9.7 |
| HDL (mg/dL) | 60.0±5.2 | 56.2±5.4 | 51.5±8.3 | 49.0±10.3 | 43.8±6.7a |
| LDL (mg/dL) | 12.7±1.6 | 13.5±1.9 | 13.2±2.6 | 14.7±4.3 | 13.7±2.5 |
Values are expressed as the mean±standard error of the mean (n=6). Serum biochemical indexes were analyzed using a biochemical analyzer.
CO: costunolide, DCL: dehydrocostus lactone, AST: aspartate aminotransferase, ALP: alkaline phosphatase, HDL: high density lipoprotein, LDL: low density lipoprotein.
ap<0.05 compared to the benign prostate hyperplasia (BPH) group. Statistical analyses were performed using ANOVA and Dunnett's multiple comparison test.