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. 2021 Mar 25;11:6862. doi: 10.1038/s41598-021-85811-4

Table 3.

Effects of concussion on integrated measures of mean betweenness centrality (ICBavg), mean eigenvector centrality (ICEavg), modularity (IMOD) and degree assortativity (IDAS), for concussed athletes at acute injury (ACU), return to play (RTP) and one year post-RTP (1YR). This includes cross-sectional differences relative to controls (CTL) and within-subject longitudinal changes between imaging sessions. Tables report bootstrap ratios (BSRs) and p-values. Significant effects at an FDR threshold of 0.05 are noted with ‘*’.

ICBavg ICEavg IMOD IDAS
BSR p BSR p BSR p BSR p
Cross-sectional ACU-CTL 0.44 0.718 1.64 0.108 2.22 0.029 − 1.57 0.111
RTP-CTL 0.36 0.677 1.07 0.273 − 0.31 0.725 − 0.27 0.806
1YR-CTL 2.23 0.040 − 0.88 0.367 − 0.54 0.561 2.01 0.044
Longitudinal RTP-ACU − 0.11 0.134 − 0.49 0.614 − 2.69 0.009* 1.15 0.254
1YR-ACU 1.60 0.118 − 2.00 0.042 − 2.31 0.025* 2.78 0.010*
1YR-RTP 1.56 0.938 − 1.63 0.100 − 0.24 0.805 2.05 0.034*
CS1 regression ACU − 0.31 0.721 0.19 0.816 0.84 0.382 − 0.83 0.372
RTP 0.85 0.386 − 0.70 0.495 1.05 0.261 0.52 0.592
1YR − 2.55 0.013* 0.27 0.823 − 2.97 0.003* − 0.21 0.857
CS2 regression ACU 0.55 0.541 0.38 0.710 − 0.33 0.731 − 0.61 0.548
RTP 0.87 0.378 1.24 0.226 0.14 0.939 − 1.21 0.224
1YR 0.89 0.349 − 2.24 0.033 − 0.99 0.355 1.76 0.106