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. 2021 Mar 12;12:639491. doi: 10.3389/fimmu.2021.639491

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Copyright © 2021 Berke, Sun, Ong, Sanati, Huffman, Brunson, Loney, Ostrow, Racz, Zhao, Xiang, Masci, Zheng, Wu and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene and pathway level comparison between Scherer et al. (14) and Gaucher et al. (15). Both studies analyzed YF-Vax-induced immune responses in vaccinated human subjects. The comparison between these two studies based on: (A) numbers of significant genes; (B) enriched Reactome pathways based on both unique and shared genes; and (C) enriched Reactome pathways based on only unique genes (Note that 110 genes in A were not included for this analysis). Even when no shared genes are analyzed, many pathways are shared as seen in (C).